The greatest antiplasmodial activity was observed in the ethyl acetate crude extract. Carica papaya is widely grown now and used in different for the purpose of food as well as decorative purpose. The antioxidant effect of fermented papaya preparation in. Carica papaya, aerial parts, anticancer activity, phytoconstituents.
Pusa dwarf linn jyotsna kiran peter, yashab kumar, priyanka pandey and harison masih department of microbiology and fermentation technology, jsbb, shiats deemed to be university, naini, up, india 211008. Introduction cancer is a leading cause of death worldwide, it is a dreadful disease, and combating this disease is of great importance to public health. Carica is a genus of flowering plants in the family caricaceae including c. Carica papaya cp otherwise known as the papaya pear is found in most tropical and subtropical countries of the world. Caricaceae is a genus of rapid growing unbranched small trees, native to tropical america and widely distributed in the tropics. The melons are usually picked in a green state and allowed to ripen. The fruits of papaya are much sought after by human as valuable foodstuff and have antihypertensive activity. Antioxidant activity of fermented papaya preparation fpp in the absence and presence of saliva. Experimental animals received 25200 mgkg orally of the extracts or saline control group and the reference group received 5 mg kg of indomethacin. For each extract a phytochemical screening was performed. Pdf pawpaw carica papaya linn seeds, peels and leaves are well known for their medicinal and potent pharmacological values. The purpose of this paper is to investigate various extracts of annona squamosa l annonanceae and carica papaya l caricaceae seeds for their antioxidant activity, free radical scavenging ability, total phenolic and flavonoid contents.
Sd on the phytochemicals composition and antioxidant activities of carica papaya seeds, a medicinal plant, was investigated. Pdf northeast india is rich in medicinal plants and is unique in the diversity and. Carica papaya is widely used in folk medicine as herbal remedy to prevent, protect against, and cure several diseases. Carica papaya, solo, solomix, antimicrobial, antioxidant 1.
Antifungal activity of carica papaya linkedin slideshare. These curative properties are based on the presence in different parts of the plant of phytochemical nutrients with antioxidant effect. Models of acute gastric ulcer induction by ethanol and indomethacin and of chronic ulcer by acetic acid were used. The gastric juice and mucus parameters were evaluated using the. Antibacterial activity of seed and leaf extract of carica. Phytochemical screening and hypoglycemic activity of. An overview vijay yogiraj, pradeep kumar goyal, chetan singh chauhan, anju goyal, bhupendra vyas abstract papaya carica papaya linn is commonly called as pawpaw and it belongs to the family caricaceae. We investigated the antiplasmodial properties of crude extracts from carica papaya leaves to trace the activity through bioassayguided fractionation. The highland papayas, vasconcellea, are considered the nearest relatives to carica papaya although the relationship is not close aradhya et al. Antifungal activity in ethanolic extracts of carica papaya. This fruit, however, is now found yearround throughout tropical and equatorial regions.
The medicinal properties of papaya fruit and other parts of the plant are also well known in traditional system of medicine. The results showed that the highest antioxidant activity through. This study was designed to explore the preliminary phytochemical and physicochemical analysis of carica papaya l. Antioxidant analysis of different parts of carica papaya. Pdf nutraceutical and antioxidant properties of the seeds, leaves. Phytochemical screening and hypoglycemic activity of carica papaya leaf in streptozotocininduced diabetic rats. Papaya is an economically important fruit crop in hawaii. The effect of in vitro digestion on the antioxidant activity of fruit. Antioxidant activity of papaya seed extracts article pdf available in molecules 168. Mountain papayas carica pubescens spread limitedly and can only adapt in the highland environment. We found that the antioxidant activity of vitamin c and carica papaya seeds extract is high when added during the recovery after oxidative stress for vitamin c and during oxidative stress for carica papaya seeds extract. At concentration of 200 papaya seed extract, papaya peel extract exhibited a gml, the te values decreased significantly in the significantly higher p inhibition activity at the order of bha 1478 1. Since, each part of papaya tree possesses economic value, it is grown on commercial scale.
The present study evaluated the antioxidant and immunostimulant activities of carica papaya l aqueous extract against acrylamide toxicity. Fruit harvest produces various byproducts as plants are removed after finishing the production cycle approximately 2 years of continuous. In some parts of asia, the young leaves of the papaya are steamed and eaten like spinach. Ginsburg2 1the hematology branch, hebrew university hadassah medical center, jerusalem, israel 2the institute for dental sciences, faculty of dental medicine, hebrew university hadassah medical center, jerusalem, israel oxidative stress has been recognized to play. Potential test of papaya leaf and seed extract carica papaya as larvicides against anopheles mosquito larvae mortality. The larvicidal activity of selected parts of carica papaya extracts against aedesaegypti are given in table 2. The antioxidant effect of fermented papaya preparation in the oral cavity q1 e. Diabetes the killer disease known worldwide has been implicated to generate oxidative stress and carica papaya has been suggested to manage this effect. Sp in jayapura, papua indonesia henny sesanti1, arsunan, a. Phytochemical screening, antimicrobial and antioxidant. Antiulcerogenic activity of carica papaya seed in rats. The papaya plant, carica papaya careica papiuh, is a shortlived herbaceous plant native to tropical climates in the americas. Phytochemical screening, antioxidant activity, and. The antioxidant activities of solo and solomix showed ic50 of 1.
The present study was conducted to evaluate the antioxidant and immunostimulant effects of the carica papaya fruit aqueous extract cpf, caricaceae against acrylamide induced oxidative stress and improvement of immune functions which affected by free radicals liberating acrylamide in rats. Carica papaya seed isolates and concentrate demonstrated potent antioxidant activity and could be of nutraceutical importance in the pharmaceutical and food. Carica papaya have been reported to posses potent mosquito larvicidal activity. Antihypertensive effect of carica papaya via a reduction in ace activity and improved baroreflex.
Papaya as an alternative antibiotic for the development of newer antibacterial agents. Antibacterial activity of seed and leaf extract of carica papaya var. Potential test of papaya leaf and seed extract carica. Pharmacological activity of each division of carica papaya whole carica papaya has a unique pharmacological uses 4. Cells posses a variety of primary and secondary defenses against lipid peroxidation and other deleterious effect of oxidative damage. This family comprises of 31 species in the four genera. Papayas are the fourth most traded tropical fruit following. A2 and hasanuddin ishak3 1 environmental health department, polytechnic of health, jayapura, papua province, indonesia. The antioxidant activity was studied at 517 nm by dpph free radical scavenging activity.
Papaya is commonly known for its food and nutritional values throughout the world. When ripe, the flesh is sweet and juicy and similar in taste to other melons. Caricaceae papaya originates from tropical central and south america, ranging from mexico to bolivia. The antiinflammatory activity of an ethanolic extract of carica papaya leaves was investigated in rats using carrageenan induced paw oedema, cotton pellet granuloma and formaldehyde induced arthritis models. The results showed petroleum ether extract of the rind of raw carica papaya fruit exhibited significant anti malarial activity. About four species are found of which carica papaya, linn. Papaya is a small, bushy tree with a hollow trunk, large palmate leaves, and oblong smoothskinned fruits melons.
Introduction to papaya, carica papaya, as a food of the. About the classification report about the classification download. Effect of drying methods on the phytochemicals composition. Papayas uc davis western institute for food safety and. Pdf an investigation of the antioxidant property of carica papaya. But the home of the papaya is tropical latin america.
Drying methods had significant p antioxidant phytochemicals, that is, total phenol, tannin, total flavonoid, total carotenoid, and vitamin c levels of the seeds, with freezedrying. Classification for kingdom plantae down to species carica papaya l. The spectrophotometer absorbance at 595nm for the carica papaya extract is given in table 2. Casein assay wavelength enzyme activity carica papaya ananas comosus actinidia deliciosa 280 280 280 2. Effects of drying on total polyphenols content and antioxidant. In vivo antiprotozoal activity of the chloroform extract from carica papaya seeds against amastigote stage of trypanosoma cruzi during indeterminate and. As a crop, papaya is characterized by high yield and precociousness since it begins scaled production before the first year. Evaluation of mosquito larvicidal effect of carica coden. Click on names to expand them, and on p for plants profiles. Carica papaya, belongs to the family of caricaceae, and several. Administration dependent antioxidant effect of carica. Pdf antioxidant activity of seed extracts of annona. Pdf antioxidant potential of carica papaya peel and seed. This study demonstrates the efficacy of ethanolic leaf extracts of c.
Antioxidant analysis of different parts of carica papaya abstract this study was conducted to compare the total antioxidant activity taa, total phenolic content tpc and total flavonoid content tfc from the different parts of papaya tree including their ripe and unripe fruit, seeds and the young leaves. Antioxidant activity of seed extracts of annona squamosa and carica papaya. U v vis spectral analysis was done by using u v vis spectrophotometer between 300nm. The purpose of the present study was to evaluate the gastroprotective and healing effects of the methanolic extract of the seed of the papaya carica papaya l. Carica papaya, alkaloids, antioxidants, antehelminthes, herbs 1.
Ms showed at least 15 components, esters were the most abundant group of compounds. In some parts of the world, specially australia and some islands of the west indies, it is known as papaw, or pawpaw, names which are better limited to the very different, mainly wild asimina triloba dunal, belonging to the annonaceae. Studies on the effect of the different modes of extraction. Introduction biological activity is the basis for traditional medicine, which uses the pharmacological efficacy of natural compounds present in herbal preparations for treating human diseases 1. Introduction medicinal plant is an important element of indigenous medical systems in all over the world. Papayas are a fleshy fruit that were nicknamed tree melons by early european explorers, but papaya fruit is actually considered to be a berry. Silver nanoparticles from unripe carica papaya fruit and its antibacterial activity i u vvis spectra analysis the reduction of pure silver ions was monitored by measuring the u v vis spectrum of reaction mixture at 5 hours.
Papaya is the most widely cultivated and best known species. Abstract background papaya is widely grown in malaysia and. This study was therefore aimed at evaluating the antioxidant activity of c. Casein assay subathra et al 2012 the enzyme activity of the crude enzyme extracts was determined. Antiinflammatory activities of ethanolic extract of.
Anticancer activity of carica papaya extracts in and. Carica papaya caricaceae is believed to probably originate from southern mexico and costa rica and then introduced as a plantation crop in all tropical and subtropical regions krishna et al. The mosquito larvicidal activity reported in the present study could be due to any of the bioactive compounds mentioned above. Antioxidant effect of aqueous carica papaya seeds extract. Effect of carica papaya leaf extract capsule on platelet. Review on nutritional, medicinal and pharmacological. Administration dependent antioxidant effect of carica papaya. Two methods namely dpph radical scavenging keywords antioxidant activity total phenolic content total flavonoid content carica papaya.